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Assay Detail

CHEMBL2013788

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FGFR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors.
Oza V, Ashwell S, Brassil P, Breed J, Ezhuthachan J, Deng C, Grondine M, Horn C, Liu D, Lyne P, Newcombe N, Pass M, Read J, Su M, Toader D, Yu D, Yu Y, Zabludoff S.
Bioorg Med Chem Lett (2012) 22 : 2330 -2337
PubMed 22342147 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.42 6.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2012881 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2012881 IC50 = 385.0 nM 6.42