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Assay Detail

CHEMBL2013946

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of tubulin polymerization
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of novel 7-oxo and 7-hydroxy trifluoroallocolchicinoids with cytotoxic effect.
Chosson E, Santoro F, Rochais C, Santos JS, Legay R, Thoret S, Cresteil T, Sinicropi MS, Besson T, Dallemagne P.
Bioorg Med Chem (2012) 20 : 2614 -2623
PubMed 22429510 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1985898 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1985898 IC50 = 700.0 nM 6.16