Assay Detail
Functional
CHEMBL2014055
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Cytotoxicity against human K562 cells treated for 4 hrs followed irradiated with invisible light for 1000 seconds by by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phaeosphaerins A-F, cytotoxic perylenequinones from an endolichenic fungus, Phaeosphaeria sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.71 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL330348 | HYPOCRELLIN A | — | 1 | 6.26 |
| CHEMBL2011656 | PHAEOSPHAERIN C | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL330348 | HYPOCRELLIN A | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL2011656 | PHAEOSPHAERIN C | IC50 | = | 7080.0 | nM | 5.15 |