Assay Detail
Binding
CHEMBL2014106
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Inhibition of mushroom tyrosinase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Depigmenting activity of new kojic acid derivative obtained as a side product in the synthesis of cinnamate of kojic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.07 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2012553 | — | — | 1 | 5.82 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.31 |
| CHEMBL2012552 | — | — | 1 | - |
| CHEMBL2012554 | — | — | 1 | - |
| CHEMBL2012555 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2012553 | — | IC50 | = | 1530.0 | nM | 5.82 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 48520.0 | nM | 4.31 |
| CHEMBL2012552 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL2012554 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2012555 | — | IC50 | > | 100000.0 | nM | - |