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Assay Detail

CHEMBL2014384

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNA gyrase B
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B.
Brvar M, Perdih A, Hodnik V, Renko M, Anderluh G, Jerala R, Solmajer T.
Bioorg Med Chem (2012) 20 : 2572 -2580
PubMed 22444877 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL36506 NOVOBIOCIN 4.0 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL36506 NOVOBIOCIN IC50 = 3.0 nM 8.52