Assay Detail
Binding
CHEMBL2014553
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Inhibition of mushroom tyrosinase
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Adamantyl N-benzylbenzamide: new series of depigmentation agents with tyrosinase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.94 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2011797 | — | — | 1 | 6.52 |
| CHEMBL2011798 | — | — | 1 | 6.40 |
| CHEMBL2011795 | — | — | 1 | 6.10 |
| CHEMBL2011796 | — | — | 1 | 6.05 |
| CHEMBL205299 | — | — | 1 | 6.05 |
| CHEMBL2011799 | — | — | 1 | 6.05 |
| CHEMBL2011794 | — | — | 1 | 5.96 |
| CHEMBL2011800 | — | — | 1 | 5.85 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2011797 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL2011798 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL2011795 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL2011796 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL205299 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL2011799 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL2011794 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2011800 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 32000.0 | nM | 4.50 |