Assay Detail
Functional
CHEMBL2014555
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Antimelanogenic activity in mouse B16 cells assessed as inhibition of melanogenesis
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Adamantyl N-benzylbenzamide: new series of depigmentation agents with tyrosinase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.07 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2011796 | — | — | 1 | 5.96 |
| CHEMBL2011795 | — | — | 1 | 5.75 |
| CHEMBL2011798 | — | — | 1 | 4.85 |
| CHEMBL450195 | RUCINOL | — | 1 | 4.70 |
| CHEMBL205299 | — | — | 1 | 4.57 |
| CHEMBL2011797 | — | — | 1 | 4.56 |
| CHEMBL2011801 | — | — | 1 | - |
| CHEMBL2011802 | — | — | 1 | - |
| CHEMBL2011803 | — | — | 1 | - |
| CHEMBL287556 | KOJIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2011796 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2011795 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL2011798 | — | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL450195 | RUCINOL | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL205299 | — | IC50 | = | 26700.0 | nM | 4.57 |
| CHEMBL2011797 | — | IC50 | = | 27600.0 | nM | 4.56 |
| CHEMBL2011801 | — | IC50 | - | — | - | |
| CHEMBL2011802 | — | IC50 | - | — | - | |
| CHEMBL2011803 | — | IC50 | - | — | - | |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 500000.0 | nM | - |