Assay Detail
Functional
CHEMBL2015272
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PANC1 cells after 96 hrs by trypan blue exclusion assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2',4',6'-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2013119 | RIGOSERTIB SODIUM | 3.0 | 1 | 7.40 |
| CHEMBL1771376 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2013119 | RIGOSERTIB SODIUM | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1771376 | — | IC50 | - | — | - |