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Assay Detail

CHEMBL2015883

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 1 (CHEMBL308)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Exploring aigialomycin d and its analogues as protein kinase inhibitors for cancer targets.
Xu J, Chen A, Go ML, Nacro K, Liu B, Chai CL.
ACS Med Chem Lett (2011) 2 : 662 -666
PubMed 24900361 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1173442 AIGIALOMYCIN D 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1173442 AIGIALOMYCIN D IC50 = 6000.0 nM 5.22