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Assay Detail

CHEMBL2016147

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Uncompetitive inhibition of COX2 by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Prostaglandin G/H synthase 2 (CHEMBL230)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N-Caffeoyl serotonin as selective COX-2 inhibitor.
Takahashi T, Miyazawa M.
Bioorg Med Chem Lett (2012) 22 : 2494 -2496
PubMed 22386242 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.18 4.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL559089 N-CAFFEOYLSEROTONIN 1 4.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL559089 N-CAFFEOYLSEROTONIN Ki = 65500.0 nM 4.18