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Assay Detail

CHEMBL2019568

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai.
Kim EL, Li JL, Dang HT, Hong J, Lee CO, Kim DK, Yoon WD, Kim E, Liu Y, Jung JH.
Bioorg Med Chem Lett (2012) 22 : 3126 -3129
PubMed 22483395 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.10 5.10
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL411729 CYTOCHALASIN B 2 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL411729 CYTOCHALASIN B IC50 = 7900.0 nM 5.10
CHEMBL411729 CYTOCHALASIN B Inhibition - % -