Assay Detail

CHEMBL2020131

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Functional

Antiviral activity against Respiratory syncytial virus

ChEMBL ↗

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Target

Respiratory syncytial virus (CHEMBL612679) ↗

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Respiratory syncytial virus (CHEMBL612679) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Respiratory syncytial virus

CHEMBL612679

Anchored from Assay target.

Protein identity Respiratory syncytial virus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Respiratory syncytial virus
Confidence	1 — Organism
Curated By	Autocuration

Target

Respiratory syncytial virus (CHEMBL612679) ↗

Type	ORGANISM
Organism	Respiratory syncytial virus

Publication

Host-directed Inhibitors of Myxoviruses: Synthesis and in vitro Biochemical Evaluation.

Sun A, Ndungu JM, Krumm SA, Yoon JJ, Thepchatri P, Natchus M, Plemper RK, Snyder JP.
ACS Med Chem Lett (2011) 2 : 798 -803
PubMed 22328961 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.00	8.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2017637	—	—	1	8.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2017637	—	EC50	=	10.0	nM	8.00