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Assay Detail

CHEMBL2020198

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Measles virus MVi/Alaska USA/16.00 genotype H2 infected in african green monkey Vero cells measured 28 to 36 hrs post infection by cell based virus yield reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Measles morbillivirus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Measles morbillivirus (CHEMBL613738)
Type ORGANISM
Organism Measles morbillivirus

Publication

Host-directed Inhibitors of Myxoviruses: Synthesis and in vitro Biochemical Evaluation.
Sun A, Ndungu JM, Krumm SA, Yoon JJ, Thepchatri P, Natchus M, Plemper RK, Snyder JP.
ACS Med Chem Lett (2011) 2 : 798 -803
PubMed 22328961 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2017637 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2017637 EC50 = 30.0 nM 7.52