Assay Detail
Binding
CHEMBL2020487
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Binding affinity to kappa opioid receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton and their pharmacologies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.80 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2016680 | — | — | 1 | 9.96 |
| CHEMBL267495 | NALFURAFINE | 4.0 | 1 | 9.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2016680 | — | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL267495 | NALFURAFINE | Ki | = | 0.23 | nM | 9.64 |