Assay Detail
Functional
CHEMBL2020795
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Antiproliferative activity against human MCF7 cells after 48 hrs by CellTiter-GloTM assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Analogs of the RSK inhibitor SL0101: optimization of in vitro biological stability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.30 | 4.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017518 | — | — | 1 | 4.47 |
| CHEMBL240954 | — | — | 1 | 4.34 |
| CHEMBL2017519 | — | — | 1 | 4.33 |
| CHEMBL2017520 | — | — | 1 | 4.27 |
| CHEMBL2017517 | — | — | 1 | 4.11 |
| CHEMBL2017523 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017518 | — | IC50 | = | 34100.0 | nM | 4.47 |
| CHEMBL240954 | — | IC50 | = | 45600.0 | nM | 4.34 |
| CHEMBL2017519 | — | IC50 | = | 46400.0 | nM | 4.33 |
| CHEMBL2017520 | — | IC50 | = | 53300.0 | nM | 4.27 |
| CHEMBL2017517 | — | IC50 | = | 77000.0 | nM | 4.11 |
| CHEMBL2017523 | — | IC50 | > | 100000.0 | nM | - |