Assay Detail
Functional
CHEMBL2024823
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at alpha1 nAChR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Acetylcholine receptor subunit alpha (CHEMBL4808) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2022495 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2022495 | — | IC50 | = | 3981.07 | nM | 5.40 |