Assay Detail
Binding
CHEMBL2024939
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Binding affinity to His6-tagged recombinant human PKCdelta S472D mutant by fluorescence anisotropy assay in presence of Ca2+ and lipid activator cocktail
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Conjugates of 5-isoquinolinesulfonylamides and oligo-D-arginine possess high affinity and selectivity towards Rho kinase (ROCK).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.38 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2023841 | — | — | 1 | 9.38 |
| CHEMBL2023845 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2023841 | — | Kd | = | 0.42 | nM | 9.38 |
| CHEMBL2023845 | — | Kd | - | — | - |