Assay Detail
Binding
CHEMBL2024944
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Binding affinity to SGK1 by fluorescence anisotropy assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase Sgk1 (CHEMBL2343) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Conjugates of 5-isoquinolinesulfonylamides and oligo-D-arginine possess high affinity and selectivity towards Rho kinase (ROCK).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.55 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2023841 | — | — | 1 | 7.55 |
| CHEMBL2023845 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2023841 | — | Kd | = | 28.0 | nM | 7.55 |
| CHEMBL2023845 | — | Kd | - | — | - |