Assay Detail
Binding
CHEMBL2025258
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Inhibition of Aurora A
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 5 | - | - |
| IC50 | 1 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2022968 | DUBERMATINIB | 2.0 | 1 | 8.52 |
| CHEMBL2022973 | — | — | 1 | - |
| CHEMBL2022974 | — | — | 1 | - |
| CHEMBL2022975 | — | — | 1 | - |
| CHEMBL2023345 | — | — | 1 | - |
| CHEMBL2023346 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2022968 | DUBERMATINIB | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL2022973 | — | Inhibition | - | % | - | |
| CHEMBL2022974 | — | Inhibition | - | % | - | |
| CHEMBL2022975 | — | Inhibition | - | % | - | |
| CHEMBL2023345 | — | Inhibition | - | % | - | |
| CHEMBL2023346 | — | Inhibition | - | % | - |