Assay Detail
Functional
CHEMBL2025702
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Antiviral activity against Hepatitis C virus assessed as inhibition of viral replication by replicon assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.23 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2023964 | — | — | 1 | 7.16 |
| CHEMBL1077334 | — | — | 1 | 7.14 |
| CHEMBL590851 | — | — | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2023964 | — | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL1077334 | — | EC50 | = | 72.0 | nM | 7.14 |
| CHEMBL590851 | — | EC50 | = | 41000.0 | nM | 4.39 |