Assay Detail
ADMET
CHEMBL2027142
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Cytotoxicity against human MCF7 cells expressing antioxidant response element assessed as LDH release after 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A synthetic chalcone as a potent inducer of glutathione biosynthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.54 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL252869 | — | — | 1 | 4.60 |
| CHEMBL1255773 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL252869 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL1255773 | — | IC50 | = | 33000.0 | nM | 4.48 |