Assay Detail
Binding
CHEMBL2032487
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Inhibition of VEGFR2
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| INH | 1 | - | - |
| Ki | 1 | 6.99 | 6.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404881 | — | — | 1 | 6.99 |
| CHEMBL2031893 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404881 | — | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL2031893 | — | INH | = | 6.2 | nM | - |