Assay Detail
Functional
CHEMBL2032863
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at rhesus monkey MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Macaca mulatta |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Melanin-concentrating hormone receptor 1 (CHEMBL2029193) ↗| Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
Publication
Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.10 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2032049 | — | — | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2032049 | — | IC50 | = | 0.8 | nM | 9.10 |