Assay Detail
Binding
CHEMBL2037968
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]Pyrilamine from human H1 histamine receptor by liquid scintillation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.31 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2037528 | — | — | 1 | 7.34 |
| CHEMBL2037531 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2037528 | — | Ki | = | 46.0 | nM | 7.34 |
| CHEMBL2037531 | — | Ki | = | 52.0 | nM | 7.28 |