Assay Detail
Binding
CHEMBL2038013
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PIM-mediated BAD S112 phosphorylation in human HEL92.1.7 cells after overnight incubation by ELISA
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The design, synthesis, and biological evaluation of PIM kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.76 | 5.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2035632 | — | — | 1 | 5.98 |
| CHEMBL2030386 | — | — | 1 | 5.91 |
| CHEMBL2035638 | — | — | 1 | 5.71 |
| CHEMBL2035635 | — | — | 1 | 5.62 |
| CHEMBL2030388 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2035632 | — | IC50 | = | 1051.0 | nM | 5.98 |
| CHEMBL2030386 | — | IC50 | = | 1218.0 | nM | 5.91 |
| CHEMBL2035638 | — | IC50 | = | 1963.0 | nM | 5.71 |
| CHEMBL2035635 | — | IC50 | = | 2412.0 | nM | 5.62 |
| CHEMBL2030388 | — | IC50 | = | 2582.0 | nM | 5.59 |