Assay Detail
Binding
CHEMBL2038290
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DGAT1-mediated triacylglycerol synthesis in human HuTu80 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HuTu80 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.30 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2036730 | — | — | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2036730 | — | IC50 | = | 0.5 | nM | 9.30 |