Assay Detail
Binding
CHEMBL2039412
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human PDK1 assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation counting
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3-phosphoinositide-dependent protein kinase 1 (CHEMBL2534) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.71 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | 2.0 | 1 | 5.18 |
| CHEMBL492828 | ISOXANTHOHUMOL | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL492828 | ISOXANTHOHUMOL | IC50 | = | 58700.0 | nM | 4.23 |