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Assay Detail

CHEMBL2039424

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human RAD51 in absence of ATP by SPR method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA repair protein RAD51 homolog 1 (CHEMBL2034807)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of homologous recombination in human cells by targeting RAD51 recombinase.
Huang F, Mazina OM, Zentner IJ, Cocklin S, Mazin AV.
J Med Chem (2012) 55 : 3011 -3020
PubMed 22380680 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.25 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1567670 1 5.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1567670 Kd = 5600.0 nM 5.25