Assay Detail
Functional
CHEMBL2039747
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against blood stage form of Plasmodium falciparum 3D7 infected in human erythrocytes after 48 hrs by SYBR Green-based fluorometry
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.47 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2036059 | — | — | 1 | 5.68 |
| CHEMBL2036060 | — | — | 1 | 5.68 |
| CHEMBL2036056 | — | — | 1 | 5.42 |
| CHEMBL2036057 | — | — | 1 | 5.30 |
| CHEMBL2036058 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2036059 | — | IC50 | = | 2080.0 | nM | 5.68 |
| CHEMBL2036060 | — | IC50 | = | 2080.0 | nM | 5.68 |
| CHEMBL2036056 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL2036057 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2036058 | — | IC50 | = | 5560.0 | nM | 5.25 |