Assay Detail
Binding
CHEMBL2045828
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Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.82 | 7.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273807 | — | — | 1 | 7.98 |
| CHEMBL1814066 | — | — | 1 | 5.87 |
| CHEMBL1814064 | — | — | 1 | 5.54 |
| CHEMBL1814065 | — | — | 1 | 5.24 |
| CHEMBL1814067 | — | — | 1 | 5.19 |
| CHEMBL1643120 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273807 | — | Ki | = | 10.39 | nM | 7.98 |
| CHEMBL1814066 | — | Ki | = | 1350.0 | nM | 5.87 |
| CHEMBL1814064 | — | Ki | = | 2890.0 | nM | 5.54 |
| CHEMBL1814065 | — | Ki | = | 5820.0 | nM | 5.24 |
| CHEMBL1814067 | — | Ki | = | 6390.0 | nM | 5.19 |
| CHEMBL1643120 | — | Ki | = | 8510.0 | nM | 5.07 |