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Assay Detail

CHEMBL2045831

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of LPS/INFgamma-induced nitric oxide production in CD-1 mouse peritoneal macrophages after 48 hrs by Griess reaction
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Peritoneal macrophage cell
Confidence 1 — Organism
Curated By Autocuration

Publication

New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714.
Pozo-Rodrigálvarez A, Gradillas A, Serrano J, Fernández AP, Martínez-Murillo R, Pérez-Castells J.
Eur J Med Chem (2012) 54 : 439 -446
PubMed 22703704 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Inhibition 1 - -
IC50 1 6.09 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1800346 2 6.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1800346 IC50 = 820.0 nM 6.09
CHEMBL1800346 Inhibition - % -