Assay Detail
Functional
CHEMBL2049534
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Antiproliferative activity against human HT-29 cells after 48 hrs by MTS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.82 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378544 | VINBLASTINE SULFATE | 4.0 | 1 | 4.95 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.80 |
| CHEMBL179512 | DEMETHOXYCURCUMIN | — | 1 | 4.71 |
| CHEMBL471074 | — | — | 1 | - |
| CHEMBL470049 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378544 | VINBLASTINE SULFATE | IC50 | = | 11180.0 | nM | 4.95 |
| CHEMBL140 | CURCUMIN | IC50 | = | 15900.0 | nM | 4.80 |
| CHEMBL179512 | DEMETHOXYCURCUMIN | IC50 | = | 19380.0 | nM | 4.71 |
| CHEMBL471074 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL470049 | — | IC50 | > | 150000.0 | nM | - |