Assay Detail
Functional
CHEMBL2050468
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Cytotoxicity against human SKLU1 cells assessed as growth inhibition after 48 hrs by SRB assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-LU-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enantiomeric derivatives of tokinolide B: absolute configuration and biological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.43 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL338474 | HELENALIN | — | 1 | 6.68 |
| CHEMBL2047347 | — | — | 1 | 5.39 |
| CHEMBL2047350 | — | — | 1 | 5.37 |
| CHEMBL2047349 | — | — | 1 | 5.31 |
| CHEMBL2047348 | — | — | 1 | 5.23 |
| CHEMBL2047345 | — | — | 1 | 5.15 |
| CHEMBL2047346 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL338474 | HELENALIN | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL2047347 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL2047350 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL2047349 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL2047348 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL2047345 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL2047346 | — | IC50 | = | 13200.0 | nM | 4.88 |