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Assay Detail

CHEMBL2051161

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MCF7 cells after 48 hrs by [3H]-thymidine incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Hydrophobic Interactions Improve Selectivity to ERα for Ben-zothiophene SERMs.
Chalmers MJ, Wang Y, Novick S, Sato M, Bryant HU, Montrose-Rafizdeh C, Griffin PR, Dodge JA.
ACS Med Chem Lett (2012) 3 : 207 -210
PubMed 22582136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.48 7.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46937 1 7.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46937 IC50 = 33.0 nM 7.48