Assay Detail
Binding
CHEMBL2061562
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
4,4'-diapophytoene synthase (CHEMBL5440) ↗| Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus |
Publication
Head-to-head prenyl tranferases: anti-infective drug targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.13 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL561057 | SQ109 | 2.0 | 1 | 6.44 |
| CHEMBL39581 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL561057 | SQ109 | Ki | = | 360.0 | nM | 6.44 |
| CHEMBL39581 | — | Ki | = | 1500.0 | nM | 5.82 |