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Assay Detail

CHEMBL2061798

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Tacaribe virus infected in african green monkey Vero 76 cells assessed as reduction of viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mammarenavirus tacaribeense
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Tacaribe virus (CHEMBL613131)
Type ORGANISM
Organism Mammarenavirus tacaribeense

Publication

3-Bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin: synthesis and antiviral activity.
Liu C, Chen Q, Schneller SW.
Bioorg Med Chem Lett (2012) 22 : 5182 -5184
PubMed 22795626 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2059156 1 5.00
CHEMBL2059155 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2059156 EC50 = 9900.0 nM 5.00
CHEMBL2059155 EC50 < 94.0 nM -