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Assay Detail

CHEMBL2061807

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus H5N1 infected in MDCK cells assessed as reduction of viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

3-Bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin: synthesis and antiviral activity.
Liu C, Chen Q, Schneller SW.
Bioorg Med Chem Lett (2012) 22 : 5182 -5184
PubMed 22795626 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.99 6.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2059155 1 6.03
CHEMBL2059156 1 5.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2059155 EC50 = 940.0 nM 6.03
CHEMBL2059156 EC50 = 1140.0 nM 5.94