Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2065347

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of LCK
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosine-protein kinase Lck (CHEMBL258)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeted kinase selectivity from kinase profiling data.
Milletti F, Hermann JC.
ACS Med Chem Lett (2012) 3 : 383 -386
PubMed 24900482 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 7.70 9.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL406845 1 9.10
CHEMBL1090356 1 7.40
CHEMBL306380 1 7.20
CHEMBL2062938 1 7.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL406845 Ki = 0.7943 nM 9.10
CHEMBL1090356 Ki = 39.81 nM 7.40
CHEMBL306380 Ki = 63.1 nM 7.20
CHEMBL2062938 Ki = 79.43 nM 7.10