Assay Detail
Binding
CHEMBL2065461
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Inhibition of Dyrk1
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.29 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2062564 | — | — | 1 | 7.70 |
| CHEMBL2062581 | — | — | 1 | 7.22 |
| CHEMBL2062577 | — | — | 1 | 6.40 |
| CHEMBL2062563 | — | — | 1 | 6.10 |
| CHEMBL2062565 | — | — | 1 | 5.77 |
| CHEMBL2062575 | — | — | 1 | 5.58 |
| CHEMBL2062585 | — | — | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2062564 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL2062581 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL2062577 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL2062563 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL2062565 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL2062575 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL2062585 | — | IC50 | = | 5400.0 | nM | 5.27 |