Assay Detail
Binding
CHEMBL2065775
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of human MMP7 using fluorogenic substrate by Dixon plot analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.40 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1651842 | — | — | 1 | 4.74 |
| CHEMBL2063274 | — | — | 1 | 4.51 |
| CHEMBL2063273 | — | — | 1 | 4.31 |
| CHEMBL483857 | — | — | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1651842 | — | Ki | = | 18200.0 | nM | 4.74 |
| CHEMBL2063274 | — | Ki | = | 31000.0 | nM | 4.51 |
| CHEMBL2063273 | — | Ki | = | 48500.0 | nM | 4.31 |
| CHEMBL483857 | — | Ki | = | 96000.0 | nM | 4.02 |