Assay Detail
Functional
CHEMBL2065818
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against intracellular Leishmania donovani
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.42 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3216564 | — | — | 1 | 7.60 |
| CHEMBL3217216 | — | — | 1 | 7.55 |
| CHEMBL1275764 | — | — | 1 | 7.44 |
| CHEMBL3217009 | — | — | 1 | 7.10 |
| CHEMBL3216786 | — | — | 1 | - |
| CHEMBL3215673 | — | — | 1 | - |
| CHEMBL3216562 | — | — | 1 | - |
| CHEMBL3216561 | — | — | 1 | - |
| CHEMBL3216324 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3216564 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL3217216 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL1275764 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL3217009 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL3216786 | — | IC50 | - | — | - | |
| CHEMBL3215673 | — | IC50 | - | — | - | |
| CHEMBL3216562 | — | IC50 | - | — | - | |
| CHEMBL3216561 | — | IC50 | - | — | - | |
| CHEMBL3216324 | — | IC50 | - | — | - |