Assay Detail
Binding
CHEMBL2072159
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Inhibition of Plasmodium vivax PLM4 using Lys-Glu-Phe-Val-Phe-NPhe-Ala-Leu-Lys as substrate by spectrophotometry
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium vivax |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiplasmodial activities of 4-aminoquinoline-statine compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 8.80 | 9.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2069614 | — | — | 1 | 9.37 |
| CHEMBL2069613 | — | — | 1 | 9.32 |
| CHEMBL2069612 | — | — | 1 | 9.15 |
| CHEMBL1213687 | — | — | 1 | 8.92 |
| CHEMBL2069616 | — | — | 1 | 8.33 |
| CHEMBL2069615 | — | — | 1 | 7.72 |
| CHEMBL2069617 | — | — | 1 | - |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2069614 | — | Ki | = | 0.43 | nM | 9.37 |
| CHEMBL2069613 | — | Ki | = | 0.48 | nM | 9.32 |
| CHEMBL2069612 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL1213687 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL2069616 | — | Ki | = | 4.7 | nM | 8.33 |
| CHEMBL2069615 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL2069617 | — | Ki | - | — | - | |
| CHEMBL76 | CHLOROQUINE | Ki | - | — | - |