Assay Detail
Functional
CHEMBL2072162
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 after 72 hrs by parasite lactate dehydrogenase assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplasmodial activities of 4-aminoquinoline-statine compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.32 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2069613 | — | — | 1 | 7.19 |
| CHEMBL2069612 | — | — | 1 | 7.11 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.38 |
| CHEMBL2069614 | — | — | 1 | 6.32 |
| CHEMBL1213687 | — | — | 1 | 6.16 |
| CHEMBL2069617 | — | — | 1 | 5.78 |
| CHEMBL2069616 | — | — | 1 | 5.33 |
| CHEMBL2069615 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2069613 | — | IC50 | = | 64.0 | nM | 7.19 |
| CHEMBL2069612 | — | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 412.0 | nM | 6.38 |
| CHEMBL2069614 | — | IC50 | = | 474.0 | nM | 6.32 |
| CHEMBL1213687 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL2069617 | — | IC50 | = | 1675.0 | nM | 5.78 |
| CHEMBL2069616 | — | IC50 | = | 4680.0 | nM | 5.33 |
| CHEMBL2069615 | — | IC50 | > | 7000.0 | nM | - |