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Assay Detail

CHEMBL2072930

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at PPARalpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL239)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.
Pirat C, Farce A, Lebègue N, Renault N, Furman C, Millet R, Yous S, Speca S, Berthelot P, Desreumaux P, Chavatte P.
J Med Chem (2012) 55 : 4027 -4061
PubMed 22260081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.74 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2069935 1 7.22
CHEMBL565 CLOFIBRATE 4.0 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2069935 EC50 = 60.0 nM 7.22
CHEMBL565 CLOFIBRATE EC50 = 55000.0 nM 4.26