Assay Detail
Binding
CHEMBL2072947
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Inhibition of human EPHA3 using myelin basic protein as substrate after 120 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.62 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2070045 | — | — | 1 | 5.80 |
| CHEMBL2070048 | — | — | 1 | 5.43 |
| CHEMBL2070047 | — | — | 1 | - |
| CHEMBL2070050 | — | — | 1 | - |
| CHEMBL2070051 | — | — | 1 | - |
| CHEMBL2070075 | — | — | 1 | - |
| CHEMBL2070081 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2070045 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL2070048 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL2070047 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070050 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070051 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070075 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2070081 | — | IC50 | > | 10000.0 | nM | - |