Assay Detail
Functional
CHEMBL2072980
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Antiparasitic activity against Toxoplasma gondii expressing CDPK1 Gly128Met mutant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2070050 | — | — | 1 | 6.00 |
| CHEMBL2070051 | — | — | 1 | 6.00 |
| CHEMBL2070081 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2070050 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL2070051 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL2070081 | — | EC50 | = | 1000.0 | nM | 6.00 |