Assay Detail
Binding
CHEMBL2073009
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Inhibition of PI4Kbeta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.49 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1986603 | — | — | 1 | 7.40 |
| CHEMBL2069328 | — | — | 1 | 6.62 |
| CHEMBL2071338 | — | — | 1 | 6.04 |
| CHEMBL2071342 | — | — | 1 | 5.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1986603 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL2069328 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL2071338 | — | IC50 | = | 920.0 | nM | 6.04 |
| CHEMBL2071342 | — | IC50 | = | 1330.0 | nM | 5.88 |