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Assay Detail

CHEMBL2073131

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Neisseria meningitidis alpha-1,4-GalT after 15 mins by competitive binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Neisseria meningitidis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of galactosyltransferases by a novel class of donor analogues.
Descroix K, Pesnot T, Yoshimura Y, Gehrke SS, Wakarchuk W, Palcic MM, Wagner GK.
J Med Chem (2012) 55 : 2015 -2024
PubMed 22356319 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.55 4.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL439009 1 4.77
CHEMBL2070378 1 4.55
CHEMBL130266 URIDINE_DIPHOSPHATE 1 4.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL439009 IC50 = 17000.0 nM 4.77
CHEMBL2070378 IC50 = 28000.0 nM 4.55
CHEMBL130266 URIDINE_DIPHOSPHATE IC50 = 46000.0 nM 4.34