Assay Detail
Functional
CHEMBL2075322
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HeLa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier organic anion transporter family member 2A1 (CHEMBL2073703) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.53 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL815 | DINOPROST | 4.0 | 1 | 7.64 |
| CHEMBL1235252 | PROSTAGLANDIN D2 | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL815 | DINOPROST | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL1235252 | PROSTAGLANDIN D2 | Ki | = | 38.0 | nM | 7.42 |