Assay Detail
Functional
CHEMBL2076987
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.4 uM) in membrane vesicles from MRP3-expressing HEK cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | HEK293 |
| Subcellular | Membrane vesicle |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Multidrug resistance associated protein (CHEMBL2073669) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.40 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224867 | TAUROCHOLIC ACID | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224867 | TAUROCHOLIC ACID | IC50 | = | 40000.0 | nM | 4.40 |